Explain diseases that may arise as a result of protein folding dysfunction. – Essaylink

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Advanced Cell and Molecular Biology.

Protein Folding.

Describe protein folding and processing (include in your answer action of chaperones and a disease that results from a defect in protein folding) (30 marks)

Introduce protein synthesis-diversity of proteins and relate it to post modification of proteins

Protein folding-molecules involved-structure and function

(chaperones-PDI, PPI, chaperonins, Hsp70).

Explain diseases that may arise as a result of protein folding dysfunction.

Explain how the disease Alzheimer is caused by a defect in protein folding (amyloid-b protein) which causes plaques in the brain.

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